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IDP dMRI TBSS MO Middle cerebellar peduncle

near CXXC5 · rs10059371

What the study found

Who was studied 20,860 British ancestry individuals; replicated in 10,496 British ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.089 higher (95% confidence interval 0.069-0.109); p = 9 × 10−18.

How common The G allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 5, band 5q31.2 — between genes, 0.8 kb from CXXC5.

What each result means

C/C No copy of the version the research linked to IDP dMRI TBSS MO Middle cerebellar peduncle. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to IDP dMRI TBSS MO Middle cerebellar peduncle. That is a smaller link than two copies.
G/G Two copies of the version the research linked to IDP dMRI TBSS MO Middle cerebellar peduncle. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10059371

What is rs10059371?

rs10059371 is a single position in the genome, in or near the near CXXC5 gene. Published research associates it with idp dmri tbss mo middle cerebellar peduncle. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10059371 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10059371 come from?

GWAS Catalog, Nature neuroscience 2021, PMID:33875891. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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IDP dMRI TBSS MO Middle cerebellar peduncle (rs10059371). MyGeneLog™. https://www.mygenelog.com/variants/rs10059371

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