A/APublished research associates this genotype with typical/baseline likelihood of Esophageal cancer — no copies of the reported risk allele.
A/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Esophageal cancer.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Esophageal cancer compared to the general population.
rs10058728 is a single position in the genome, in or near the CSNK1A1 gene. Published research associates it with esophageal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10058728 linked to?
On MyGeneLog this position is linked to Oesophageal Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs10058728 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10058728 come from?
GWAS Catalog, Nat Genet 2011, PMID:21642993. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.