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Who was studied 426,824 British ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.019 higher (95% confidence interval 0.013-0.025); p = 6 × 10−10.
How common The G allele had a frequency of about 89% in the people studied.
Where it sits Chromosome 5, band 5q23.3 — in an intron of FBN2.
What each result means
A/ANo copy of the version the research linked to Heel bone mineral density. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Heel bone mineral density. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Heel bone mineral density. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2019 · PMID 30598549 · open access
Questions about rs10057855
What is rs10057855?
rs10057855 is a single position in the genome, in or near the FBN2 gene. Published research associates it with heel bone mineral density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10057855 linked to?
On MyGeneLog this position is linked to Heel Bone Mineral Density. The research behind each link, and its sources, are set out on that condition page.
Does having rs10057855 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10057855 come from?
GWAS Catalog, Nature genetics 2019, PMID:30598549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Heel bone mineral density (rs10057855). MyGeneLog™. https://www.mygenelog.com/variants/rs10057855