A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1).
G/GPublished research associates this genotype with typical/baseline likelihood of Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) — no copies of the reported risk allele.
The pharmacogenomics journal · 2016 · PMID 26503814 · open access
Questions about rs10056066
What is rs10056066?
rs10056066 is a single position in the genome, in or near the SGCD gene. Published research associates it with response to bronchodilator in chronic obstructive pulmonary disease (change in fev1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10056066 linked to?
On MyGeneLog this position is linked to Chronic Obstructive Pulmonary Disease (COPD). The research behind each link, and its sources, are set out on that condition page.
Does having rs10056066 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10056066 come from?
GWAS Catalog, Pharmacogenomics J 2016, PMID:26503814. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.