near RGS14 · rs10051765
Where this position leads
Condition: Urolithiasis
What the study found
Who was studied 13,746 East Asian ancestry cases, 241,425 East Asian ancestry controls, 17,969 European ancestry cases, 702,230 European ancestry controls.
The effect Each copy of the T allele carried 0.88 times the odds of Kidney stone disease (95% confidence interval 0.86-0.89); p = 4 × 10−47.
How common The T allele had a frequency of about 64% in the people studied.
Where it sits Chromosome 5, band 5q35.3 — between genes, 0.4 kb from RGS14.
rs10051765 is a single position in the genome, in or near the near RGS14 gene. Published research associates it with kidney stone disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Urolithiasis. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature communications 2025, PMID:40216741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Kidney stone disease (rs10051765). MyGeneLog™. https://www.mygenelog.com/variants/rs10051765