Gluteofemoral adipose tissue volumes (adjusted for BMI and height)
LINC02227 · rs10044492
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Who was studied 37,641 European ancestry, East Asian ancestry, South Asian ancestry, African ancestry, NR ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.048 lower (95% confidence interval 0.032-0.064); p = 5 × 10−9.
How common The C allele had a frequency of about 73% in the people studied.
Where it sits Chromosome 5, band 5q33.3 — in an intron of LINC02227.
What each result means
C/CTwo copies of the version the research linked to Gluteofemoral adipose tissue volumes (adjusted for BMI and height). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Gluteofemoral adipose tissue volumes (adjusted for BMI and height). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Gluteofemoral adipose tissue volumes (adjusted for BMI and height). This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35773277 · open access
Questions about rs10044492
What is rs10044492?
rs10044492 is a single position in the genome, in or near the LINC02227 gene. Published research associates it with gluteofemoral adipose tissue volumes (adjusted for bmi and height). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10044492 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs10044492 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10044492 come from?
GWAS Catalog, Nature communications 2022, PMID:35773277. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Gluteofemoral adipose tissue volumes (adjusted for BMI and height) (rs10044492). MyGeneLog™. https://www.mygenelog.com/variants/rs10044492