4 4922426222225Reads by AI crawlersClaude2ChatGPT2Google · Gemini4Perplexity2Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total49Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 8,506 European ancestry cases, up to 10,596 European ancestry controls.
The effect
Each copy of the G allele carried 1.40 times the odds of Type 1 diabetes; p = 3 × 10−23.
Where it sits Chromosome 11, band 11p15.5 — in an intron of INS-IGF2.
What each result means
A/ANo copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs1004446
What is rs1004446?
rs1004446 is a single position in the genome, in or near the IGF2AS gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1004446 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs1004446?
Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs1004446 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1004446 come from?
GWAS Catalog, PLoS Genet 2011, PMID:21829393. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
4 4922426222225Reads by AI crawlersClaude2ChatGPT2Google · Gemini4Perplexity2Meta AI6Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total49Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 1 diabetes (rs1004446). MyGeneLog™. https://www.mygenelog.com/variants/rs1004446