5 5652255222229Reads by AI crawlersClaude5ChatGPT2Google · Gemini2Perplexity5Meta AI5Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others29Total56Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 1,775 European ancestry choroidal neovascularization cases, 4,134 European ancestry controls; replicated in 4,515 European and unknown ancestry choroidal neovascularization cases, 15,240 European and unknown ancestry controls.
The effect
Each copy of the T allele carried 1.31 times the odds of Age-related macular degeneration (choroidal neovascularisation) (95% confidence interval 1.19-1.44); p = 6 × 10−9.
How common The T allele had a frequency of about 46% in the people studied.
Where it sits Chromosome 4, band 4q25 — in an intron of CFI.
What each result means
C/CNo copy of the version the research linked to Age-related macular degeneration (choroidal neovascularisation). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Age-related macular degeneration (choroidal neovascularisation). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Age-related macular degeneration (choroidal neovascularisation). That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs10033900
What is rs10033900?
rs10033900 is a single position in the genome, in or near the CF1 gene. Published research associates it with age-related macular degeneration (choroidal neovascularisation). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10033900 linked to?
On MyGeneLog this position is linked to Age-Related Macular Degeneration. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs10033900?
Subjects that appear in the title or abstract of the same papers as this rsID include short-sightedness and screens (3 papers), vitamins and nutrient levels (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs10033900 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10033900 come from?
GWAS Catalog, Ophthalmology 2012, PMID:22705344. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
5 5652255222229Reads by AI crawlersClaude5ChatGPT2Google · Gemini2Perplexity5Meta AI5Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others29Total56Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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