6 5212264222229Reads by AI crawlersClaude1ChatGPT2Google · Gemini2Perplexity6Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others29Total52Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 550 European ancestry cases, 4,476 European ancestry controls; replicated in 3,030 European ancestry cases, 14,780 European ancestry controls, 333 Han Chinese ancestry cases, 2,836 Han Chinese ancestry controls.
The effect
Each copy of the T allele carried 1.39 times the odds of Atrial fibrillation/atrial flutter (95% confidence interval 1.26-1.53); p = 7 × 10−11.
How common The T allele had a frequency of about 8% in the people studied.
Where it sits Chromosome 4, band 4q25 — between genes, 2.3 kb from LINC01438.
What each result means
G/GNo copy of the version the research linked to Atrial fibrillation/atrial flutter. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Atrial fibrillation/atrial flutter. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Atrial fibrillation/atrial flutter. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs10033464
What is rs10033464?
rs10033464 is a single position in the genome, in or near the PITX2 gene. Published research associates it with atrial fibrillation/atrial flutter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10033464 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs10033464?
Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (26 papers), alcohol and the flush (2 papers), sleep and insomnia (1 papers), skin, sun and hair (1 papers), blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs10033464 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10033464 come from?
GWAS Catalog, Nature 2007, PMID:17603472. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
6 5212264222229Reads by AI crawlersClaude1ChatGPT2Google · Gemini2Perplexity6Meta AI4Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others29Total52Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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