Standard

Glomerular filtration rate

SHROOM3 · rs10032549

Where this position leads

Condition: Kidney Function

rs10032549 Condition: Kidney Function Kidney Function Condition rs10032549 rs10032549 SHROOM3

What the study found

Who was studied 9,049 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.93 higher (95% confidence interval 0.62-1.24); p = 1 × 10−8.

How common The A allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 4, band 4q21.1 — in an intron of SHROOM3.

What each result means

A/A Two copies of the version the research linked to Glomerular filtration rate. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Glomerular filtration rate. That is a smaller link than two copies.
G/G No copy of the version the research linked to Glomerular filtration rate. This is the starting point the study compared everyone against.
Source

Questions about rs10032549

What is rs10032549?

rs10032549 is a single position in the genome, in or near the SHROOM3 gene. Published research associates it with glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10032549 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs10032549 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10032549 come from?

GWAS Catalog, J Hum Genet 2013, PMID:23535967. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Glomerular filtration rate (rs10032549). MyGeneLog™. https://www.mygenelog.com/variants/rs10032549

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