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Body mass index (MTAG)

FSTL5 · rs10030681

What the study found

Who was studied 694,649 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.013 higher (95% confidence interval 0.009-0.0171); p = 3 × 10−10.

Where it sits Chromosome 4, band 4q32.2 — in an intron of FSTL5.

What each result means

G/G No copy of the version the research linked to Body mass index (MTAG). This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Body mass index (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10030681

What is rs10030681?

rs10030681 is a single position in the genome, in or near the FSTL5 gene. Published research associates it with body mass index (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10030681 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10030681 come from?

GWAS Catalog, Nature communications 2022, PMID:36376304. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body mass index (MTAG) (rs10030681). MyGeneLog™. https://www.mygenelog.com/variants/rs10030681

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