Sensitive

Gastric cancer

LOC285419 · rs10029005

Where this position leads

Condition: Non-Cardia Gastric Cancer

rs10029005 Condition: Non-Cardia Gastric Cancer Non-Cardia Gastric Cancer Condition rs10029005 rs10029005 LOC285419

What the study found

Who was studied 3,771 Chinese ancestry cases, 5,426 Chinese ancestry controls; replicated in 7,035 Chinese ancestry cases, 8,323 Chinese ancestry controls.

The effect Each copy of the A allele carried 1.14 times the odds of Gastric cancer (95% confidence interval 1.10-1.19); p = 3 × 10−11.

How common The A allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 4, band 4q28.1 — in an intron of LINC02516.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gastric cancer compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gastric cancer.
G/G Published research associates this genotype with typical/baseline likelihood of Gastric cancer — no copies of the reported risk allele.
Source

Questions about rs10029005

What is rs10029005?

rs10029005 is a single position in the genome, in or near the LOC285419 gene. Published research associates it with gastric cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10029005 linked to?

On MyGeneLog this position is linked to Non-Cardia Gastric Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs10029005 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10029005 come from?

GWAS Catalog, Gut 2020, PMID:31383772. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Gastric cancer (rs10029005). MyGeneLog™. https://www.mygenelog.com/variants/rs10029005

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