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Atrial fibrillation

HAND2 · rs10024737

Where this position leads

Condition: Atrial Fibrillation

rs10024737 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs10024737 rs10024737 HAND2

What the study found

Who was studied 9,118 East Asian ancestry cases, 33,467 East Asian ancestry controls.

The effect Each copy of the C allele carried 1.33 times the odds of Atrial fibrillation (95% confidence interval 1.23-1.43); p = 2 × 10−13.

Where it sits Chromosome 4, band 4q34.1 — in the 3′ untranslated region of HAND2.

What each result means

C/C Two copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
T/T No copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
Source

Questions about rs10024737

What is rs10024737?

rs10024737 is a single position in the genome, in or near the HAND2 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10024737 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs10024737 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10024737 come from?

GWAS Catalog, Eur J Clin Invest 2021, PMID:33990960. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (rs10024737). MyGeneLog™. https://www.mygenelog.com/variants/rs10024737

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