Clozapine-to-N-desmethylclozapine metabolic ratio in schizophrenia
CTD-2005D20.1 · rs10023464
0 2372212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot7Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others12Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 3,473 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.177 lower (95% confidence interval 0.16-0.19); p = 2 × 10−91.
Where it sits Chromosome 4, band 4q13.2 — between genes, 21.9 kb from UGT2B10.
What each result means
C/CNo copy of the version the research linked to Clozapine-to-N-desmethylclozapine metabolic ratio in schizophrenia. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Clozapine-to-N-desmethylclozapine metabolic ratio in schizophrenia. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Clozapine-to-N-desmethylclozapine metabolic ratio in schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Translational psychiatry · 2020 · PMID 32555152 · open access
Questions about rs10023464
What is rs10023464?
rs10023464 is a single position in the genome, in or near the CTD-2005D20.1 gene. Published research associates it with clozapine-to-n-desmethylclozapine metabolic ratio in schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10023464 linked to?
On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.
Does having rs10023464 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10023464 come from?
GWAS Catalog, Translational psychiatry 2020, PMID:32555152. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 2372212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot7Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others12Total23Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Clozapine-to-N-desmethylclozapine metabolic ratio in schizophrenia (rs10023464). MyGeneLog™. https://www.mygenelog.com/variants/rs10023464