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Male-pattern baldness

MTHFD2L · rs10019396

What the study found

Who was studied 205,327 European ancestry males.

The effect Each copy of the A allele shifted the measure 0.03 higher (95% confidence interval 0.023-0.037); p = 2 × 10−15.

How common The A allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 4, band 4q13.3 — in an intron of MTHFD2L.

What each result means

A/A Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
G/G No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
Source

Questions about rs10019396

What is rs10019396?

rs10019396 is a single position in the genome, in or near the MTHFD2L gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10019396 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10019396 come from?

GWAS Catalog, Nature communications 2018, PMID:30573740. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Male-pattern baldness (rs10019396). MyGeneLog™. https://www.mygenelog.com/variants/rs10019396

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