Sensitive

Opioid use disorder vs exposed controls

near MIR548I2 · rs10014685

What the study found

Who was studied 1,039 European ancestry cases, 10,744 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−9.

Where it sits Chromosome 4, band 4p16.1 — between genes, 12.4 kb from MIR548I2.

What each result means

A/A Two copies of the version the research linked to Opioid use disorder vs exposed controls. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Opioid use disorder vs exposed controls. That is a smaller link than two copies.
G/G No copy of the version the research linked to Opioid use disorder vs exposed controls. This is the starting point the study compared everyone against.
Source

Questions about rs10014685

What is rs10014685?

rs10014685 is a single position in the genome, in or near the near MIR548I2 gene. Published research associates it with opioid use disorder vs exposed controls. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10014685 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10014685 come from?

GWAS Catalog, Drug and alcohol dependence 2020, PMID:32961455. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Opioid use disorder vs exposed controls (rs10014685). MyGeneLog™. https://www.mygenelog.com/variants/rs10014685

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