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Immature reticulocyte fraction (UKB data field 30280)

near LINC02260 · rs10010373

Where this position leads

Condition: Celiac Disease

rs10010373 Condition: Celiac Disease Celiac Disease Condition rs10010373 rs10010373 near LINC022…

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0147 lower (95% confidence interval 0.01-0.019); p = 3 × 10−12.

How common The A allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 4, band 4q12 — between genes, 0.8 kb from LINC02260.

What each result means

A/A Two copies of the version the research linked to Immature reticulocyte fraction (UKB data field 30280). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Immature reticulocyte fraction (UKB data field 30280). That is a smaller link than two copies.
G/G No copy of the version the research linked to Immature reticulocyte fraction (UKB data field 30280). This is the starting point the study compared everyone against.
Source

Questions about rs10010373

What is rs10010373?

rs10010373 is a single position in the genome, in or near the near LINC02260 gene. Published research associates it with immature reticulocyte fraction (ukb data field 30280). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10010373 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs10010373 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10010373 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Immature reticulocyte fraction (UKB data field 30280) (rs10010373). MyGeneLog™. https://www.mygenelog.com/variants/rs10010373

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