Standard

Age at onset of walking

near PCAT4 · rs10010217

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 70,560 European ancestry children.

The effect Each copy of the T allele shifted the measure 0.081 higher (95% confidence interval 0.056-0.106); p = 4 × 10⁻¹⁰.

How common The T allele had a frequency of about 72% in the people studied.

Where it sits Chromosome 4, band 4q21.21 — between genes, 2.3 kb from PCAT4.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Age at onset of walking — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Age at onset of walking.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Age at onset of walking compared to the general population.

Source

Genome-wide association meta-analysis of age at onset of walking in over 70,000 infants of European ancestry

Gui A, Hollowell A, Wigdor EM, Morgan MJ, Hannigan LJ, Corfield EC, Odintsova V, Hottenga JJ, Wong A, Pool R, Cullen H, Wilson S

and 16 more — show all

Warrier V, Eilertsen EM, Andreassen OA, Middeldorp CM, St Pourcain B, Bartels M, Boomsma DI, Hartman CA, Robinson EB, Arichi T, Edwards AD, Johnson MH, Dudbridge F, Sanders SJ, Havdahl A, Ronald A

Nature human behaviour · 2025 · PMID 40335706 · open access

Questions about rs10010217

What is rs10010217?

rs10010217 is a single position in the genome, in or near the near PCAT4 gene. Published research associates it with age at onset of walking. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10010217 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10010217 come from?

GWAS Catalog, Nature human behaviour 2025, PMID:40335706. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age at onset of walking (rs10010217). MyGeneLog™. https://www.mygenelog.com/variants/rs10010217

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