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Who was studied 365,954 British ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.069 higher (95% confidence interval 0.061-0.077); p = 1 × 10−54.
How common The A allele had a frequency of about 33% in the people studied.
Where it sits Chromosome 4, band 4p14 — in an intron of KLF3-AS1.
What each result means
A/ATwo copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
Frontiers in immunology · 2022 · PMID 35935937 · open access
Questions about rs1000571
What is rs1000571?
rs1000571 is a single position in the genome, in or near the KLF3-AS1 gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1000571 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs1000571 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1000571 come from?
GWAS Catalog, Frontiers in immunology 2022, PMID:35935937. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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