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Vitamin D levels

near SPOPLP3 · rs10001501

Where this position leads

Condition: Gout

rs10001501 Condition: Gout Gout Condition rs10001501 rs10001501 near SPOPLP3

What the study found

Who was studied 327,435 European ancestry individuals, 5,845 African ancestry individuals, 6,425 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0258 higher (95% confidence interval 0.02-0.032); p = 1 × 10−15.

Where it sits Chromosome 4, band 4q13.2 — between genes, 1.5 kb from SPOPLP3.

What each result means

A/A No copy of the version the research linked to Vitamin D levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Vitamin D levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Vitamin D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10001501

What is rs10001501?

rs10001501 is a single position in the genome, in or near the near SPOPLP3 gene. Published research associates it with vitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10001501 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs10001501 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10001501 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vitamin D levels (rs10001501). MyGeneLog™. https://www.mygenelog.com/variants/rs10001501

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