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Continuously updated · latest Oct 22, 2026

Lessons that are free to use in any classroom, new research, changes to the dataset, plain-language explainers, and the real genetics behind things you already know. Every entry says which subject it belongs to and what you need to know before reading it. Medical information goes stale, so entries are revised when the evidence moves — revised entries show their update date, not just the day they were first published. Every article here is CC BY-NC 4.0 licensed — free to share and adapt with credit, not for commercial use (details).

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One line of a genome data file split into its four columns — the cover for a free introductory lesson on reading raw genetic data.

Lesson: how to read a genome file, line by line

Biology Age 13+ Introductory PDF

A ready-to-run introductory genetics lesson for age 13 and up, free to use in any school, college or university. What the four columns of a genome file mean, why the last one has two letters, why a position number is meaningless without knowing which edition of the map it was measured on — and the one thing such a file can never tell you. Uses our own teaching file, never a student’s data.

Updated Sep 10, 2026 7 75

Two copies of one line of text differing by a single letter — the cover for a free classroom lesson on genes and rsIDs.

Lesson: genes and rsIDs, and what a catalogue actually measures

BiologyGenetics Age 16+ Introductory PDF

A ready-to-run genetics lesson for age 16 and up, free to use in any school, college or university. One book everybody owns a copy of: a chapter is a gene, and an rsID names a letter that differs between copies. Then students count those letters in a real catalogue and find the counts measure research attention rather than biology.

Updated Sep 9, 2026 7 68

How to read a pedigree, and where the textbook rule breaks — a free genetics lesson

Lesson: how to read a pedigree, and where the textbook rule breaks

BiologyGeneticsMathematics Age 13+ Intermediate PDF

A free genetics lesson on pedigree analysis. Three clean family trees teach the three inheritance patterns; the fourth is real, and the rule the class just learned gives the wrong answer on it.

Updated Sep 8, 2026 7 73

A dark card reading "one broken copy of two. you keep six per cent." — the cover for a free classroom chemistry lesson on multi-subunit enzymes and dominance.

Lesson: why one broken gene copy costs 94% of an enzyme

ChemistryBiologyHealth Age 16+ Intermediate PDF

A free chemistry lesson with one coin per student. Ask a class what one broken copy of a gene out of two costs you and they will say half. For this enzyme the answer is 94%, the class can compute it in twelve minutes, and the reason is the shape of the protein rather than anything in the DNA.

Updated Sep 8, 2026 8 61

A dark card reading "your calculation will be wrong. that is the lesson." — the cover for a free classroom genetics lesson on lactase persistence.

Lesson: lactose tolerance and natural selection

BiologyGeneticsStatisticsSocial studies Age 13+ Intermediate PDF

A free genetics lesson on natural selection, with no equipment needed. The class computes a prediction from real allele frequencies, gets a clean answer, and then finds out it is wrong — because the same solution evolved four separate times in the last few thousand years.

Updated Sep 7, 2026 6 67

A strip of paper on a dark background with the words "some of you will taste nothing" — the cover for a free classroom genetics lesson.

Lesson: the PTC taste test, and why the textbook version is wrong

BiologyGeneticsStatistics Age 13+ Intermediate PDF

A ready-to-run genetics lesson built on the PTC taste test — free to use in any school, college or university. Forty minutes, one paper strip, and the textbook version of the trait turns out to be wrong in a way that is more interesting than the original.

Updated Sep 7, 2026 7 92

A radioactive spider would not have done that — the real genetics behind strength, pain and climbing

The Real Genetics Behind Spider-Man

BiologyPhysicsMathematics Age 13+ Intermediate PDF

Spider-Man is back in cinemas, so here is the honest version: what each of those abilities would actually require, and what the published research says about the three that turn out to be real — in people, right now.

Updated Sep 7, 2026 10 70