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TB-LM or TBLH-BMD (pleiotropy)

near TNFSF11 · rs9525638

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of TB-LM or TBLH-BMD (pleiotropy) compared to the general population. (GWAS Catalog, Nat Commun 2017, PMID:28743860)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with TB-LM or TBLH-BMD (pleiotropy). (GWAS Catalog, Nat Commun 2017, PMID:28743860)
T/T Published research associates this genotype with typical/baseline likelihood of TB-LM or TBLH-BMD (pleiotropy) — no copies of the reported risk allele. (GWAS Catalog, Nat Commun 2017, PMID:28743860)

Source: GWAS Catalog, Nat Commun 2017, PMID:28743860

Questions about rs9525638

What is rs9525638?

rs9525638 is a single position in the genome, in or near the near TNFSF11 gene. Published research associates it with tb-lm or tblh-bmd (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs9525638 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs9525638 come from?

GWAS Catalog, Nat Commun 2017, PMID:28743860. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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