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Age-related macular degeneration

SLC16A8 · rs8135665

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Age-related macular degeneration — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2013, PMID:23455636)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Age-related macular degeneration. (GWAS Catalog, Nat Genet 2013, PMID:23455636)
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Age-related macular degeneration compared to the general population. (GWAS Catalog, Nat Genet 2013, PMID:23455636)

Source: GWAS Catalog, Nat Genet 2013, PMID:23455636

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs8135665

What is rs8135665?

rs8135665 is a single position in the genome, in or near the SLC16A8 gene. Published research associates it with age-related macular degeneration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs8135665?

Subjects that appear in the title or abstract of the same papers as this rsID include short-sightedness and screens (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs8135665 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8135665 come from?

GWAS Catalog, Nat Genet 2013, PMID:23455636. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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