A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Proximal colorectal cancer compared to the general population. (GWAS Catalog, Gut 2021, PMID:33632709)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Proximal colorectal cancer. (GWAS Catalog, Gut 2021, PMID:33632709)
G/GPublished research associates this genotype with typical/baseline likelihood of Proximal colorectal cancer — no copies of the reported risk allele. (GWAS Catalog, Gut 2021, PMID:33632709)
Source: GWAS Catalog, Gut 2021, PMID:33632709
Questions about rs80158569
What is rs80158569?
rs80158569 is a single position in the genome, in or near the BCL11B gene. Published research associates it with proximal colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs80158569 linked to?
On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs80158569 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs80158569 come from?
GWAS Catalog, Gut 2021, PMID:33632709. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.