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Standard

Odoribacter laneus abundance in stool

near GRB10 · rs76061879

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−8, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 5,959 Finnish ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.264 higher (95% confidence interval 0.17-0.36); p = 1 × 10−8.

How common The G allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 7, band 7p12.1 — between genes, 41.7 kb from GRB10.

How common each version is

AG
Japanese ToMMo
A 100.0%
World gnomAD
A 97.5% · G 2.5%
World 1000 Genomes
A 98.4% · G 1.6%
World TOPMed
A 97.2% · G 2.8%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study. No Korean figure for this position yet.

What each result means

A/A No copy of the version the research linked to Odoribacter laneus abundance in stool. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Odoribacter laneus abundance in stool. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Odoribacter laneus abundance in stool. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Quoting this page

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Odoribacter laneus abundance in stool (rs76061879). MyGeneLog™. https://www.mygenelog.com/variants/rs76061879

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