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Standard

Vertigo

near LINC02789 · rs7541515

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−8, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 48,072 European ancestry cases, 894,541 European ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 3 × 10−8.

Where it sits Chromosome 1, band 1q32.1 — between genes, 2.6 kb from LINC02789.

How common each version is

AG
Korean KRGDB
A 98.0% · G 2.0%
Korean Korea4K
A 97.8% · G 2.2%
Korean Korea1K
A 98.0% · G 2.0%
Japanese ToMMo
A 96.8% · G 3.2%
Vietnamese
A 95.8% · G 4.2%
World gnomAD
A 86.2% · G 13.8%
World 1000 Genomes
A 92.6% · G 7.4%
World TOPMed
A 87.6% · G 12.4%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

A/A No copy of the version the research linked to Vertigo. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Vertigo. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Vertigo. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Quoting this page

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Vertigo (rs7541515). MyGeneLog™. https://www.mygenelog.com/variants/rs7541515

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