Standard

Diisocyanate-induced asthma

MMP13 · rs74380195

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Diisocyanate-induced asthma — no copies of the reported risk allele. (GWAS Catalog, Toxicol Sci 2015, PMID:25918132)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diisocyanate-induced asthma. (GWAS Catalog, Toxicol Sci 2015, PMID:25918132)

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diisocyanate-induced asthma compared to the general population. (GWAS Catalog, Toxicol Sci 2015, PMID:25918132)

Source: GWAS Catalog, Toxicol Sci 2015, PMID:25918132

Questions about rs74380195

What is rs74380195?

rs74380195 is a single position in the genome, in or near the MMP13 gene. Published research associates it with diisocyanate-induced asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74380195 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74380195 come from?

GWAS Catalog, Toxicol Sci 2015, PMID:25918132. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants