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Glomerular filtration rate

SHROOM3 · rs4859682

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glomerular filtration rate compared to the general population. (GWAS Catalog, J Hum Genet 2013, PMID:23535967)
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glomerular filtration rate. (GWAS Catalog, J Hum Genet 2013, PMID:23535967)
C/C Published research associates this genotype with typical/baseline likelihood of Glomerular filtration rate — no copies of the reported risk allele. (GWAS Catalog, J Hum Genet 2013, PMID:23535967)

Source: GWAS Catalog, J Hum Genet 2013, PMID:23535967

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs4859682

What is rs4859682?

rs4859682 is a single position in the genome, in or near the SHROOM3 gene. Published research associates it with glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs4859682?

Subjects that appear in the title or abstract of the same papers as this rsID include kidneys (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs4859682 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4859682 come from?

GWAS Catalog, J Hum Genet 2013, PMID:23535967. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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