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Hepatitis C induced liver fibrosis

MERTK · rs4374383

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hepatitis C induced liver fibrosis compared to the general population. (GWAS Catalog, Gastroenterology 2012, PMID:22841784)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hepatitis C induced liver fibrosis. (GWAS Catalog, Gastroenterology 2012, PMID:22841784)
G/G Published research associates this genotype with typical/baseline likelihood of Hepatitis C induced liver fibrosis — no copies of the reported risk allele. (GWAS Catalog, Gastroenterology 2012, PMID:22841784)

Source: GWAS Catalog, Gastroenterology 2012, PMID:22841784

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs4374383

What is rs4374383?

rs4374383 is a single position in the genome, in or near the MERTK gene. Published research associates it with hepatitis c induced liver fibrosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs4374383?

Subjects that appear in the title or abstract of the same papers as this rsID include liver (7 papers), infection and immunity (6 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs4374383 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs4374383 come from?

GWAS Catalog, Gastroenterology 2012, PMID:22841784. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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