Standard

Age-related macular degeneration

CFB · rs429608

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Age-related macular degeneration — no copies of the reported risk allele. (GWAS Catalog, Proc Natl Acad Sci U S A 2010, PMID:20385819)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Age-related macular degeneration. (GWAS Catalog, Proc Natl Acad Sci U S A 2010, PMID:20385819)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Age-related macular degeneration compared to the general population. (GWAS Catalog, Proc Natl Acad Sci U S A 2010, PMID:20385819)

Source: GWAS Catalog, Proc Natl Acad Sci U S A 2010, PMID:20385819

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs429608

What is rs429608?

rs429608 is a single position in the genome, in or near the CFB gene. Published research associates it with age-related macular degeneration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs429608?

Subjects that appear in the title or abstract of the same papers as this rsID include short-sightedness and screens (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs429608 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs429608 come from?

GWAS Catalog, Proc Natl Acad Sci U S A 2010, PMID:20385819. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants