Standard

Bone mineral density

LRP5 · rs3736228

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Bone mineral density — no copies of the reported risk allele. (GWAS Catalog, Lancet 2008, PMID:18455228)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Bone mineral density. (GWAS Catalog, Lancet 2008, PMID:18455228)
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Bone mineral density compared to the general population. (GWAS Catalog, Lancet 2008, PMID:18455228)

Source: GWAS Catalog, Lancet 2008, PMID:18455228

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs3736228

What is rs3736228?

rs3736228 is a single position in the genome, in or near the LRP5 gene. Published research associates it with bone mineral density. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs3736228?

Subjects that appear in the title or abstract of the same papers as this rsID include bones and fractures (29 papers), menopause (3 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs3736228 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3736228 come from?

GWAS Catalog, Lancet 2008, PMID:18455228. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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