Sensitive

Parkinson's disease

SNCA · rs356219

Where this position leads

Condition: Parkinson's Disease

rs356219 Condition: Parkinson's Disease Parkinson's Disease Condition rs356219 rs356219 SNCA

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Parkinson's disease — no copies of the reported risk allele. (GWAS Catalog, Lancet 2011, PMID:21292315)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Parkinson's disease. (GWAS Catalog, Lancet 2011, PMID:21292315)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Parkinson's disease compared to the general population. (GWAS Catalog, Lancet 2011, PMID:21292315)

Source: GWAS Catalog, Lancet 2011, PMID:21292315

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs356219

What is rs356219?

rs356219 is a single position in the genome, in or near the SNCA gene. Published research associates it with parkinson's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs356219 linked to?

On MyGeneLog this position is linked to Parkinson's Disease. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs356219?

Subjects that appear in the title or abstract of the same papers as this rsID include anxiety and worry (1 papers), liver (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs356219 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs356219 come from?

GWAS Catalog, Lancet 2011, PMID:21292315. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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