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Complement C3 and C4 levels

C4 · rs2857009

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Complement C3 and C4 levels — no copies of the reported risk allele. (GWAS Catalog, PLoS Genet 2012, PMID:23028341)
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Complement C3 and C4 levels. (GWAS Catalog, PLoS Genet 2012, PMID:23028341)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Complement C3 and C4 levels compared to the general population. (GWAS Catalog, PLoS Genet 2012, PMID:23028341)

Source: GWAS Catalog, PLoS Genet 2012, PMID:23028341

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2857009

What is rs2857009?

rs2857009 is a single position in the genome, in or near the C4 gene. Published research associates it with complement c3 and c4 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs2857009?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2857009 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2857009 come from?

GWAS Catalog, PLoS Genet 2012, PMID:23028341. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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