A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of C-reactive protein levels compared to the general population. (GWAS Catalog, Circulation 2011, PMID:21300955)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with C-reactive protein levels. (GWAS Catalog, Circulation 2011, PMID:21300955)
G/GPublished research associates this genotype with typical/baseline likelihood of C-reactive protein levels — no copies of the reported risk allele. (GWAS Catalog, Circulation 2011, PMID:21300955)
rs2847281 is a single position in the genome, in or near the PTPN2 gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2847281 linked to?
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs2847281 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2847281 come from?
GWAS Catalog, Circulation 2011, PMID:21300955. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.