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Standard

Height

near BMP6 · rs2327010

Strength of the evidence

2 / 4

Its strongest genetic-study result is p = 10−23, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 293,593 African ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.036 higher (95% confidence interval 0.029-0.043); p = 5 × 10−24.

How common The G allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 6, band 6p24.3 — between genes, 9.2 kb from BMP6.

How common each version is

GT
Korean KRGDB
G 18.4% · T 81.6%
Korean Korea4K
G 18.6% · T 81.4%
Korean Korea1K
G 19.1% · T 81.0%
Japanese ToMMo
G 21.8% · T 78.2%
Vietnamese
G 16.7% · T 83.3%
World gnomAD
G 37.4% · T 62.6%
World 1000 Genomes
G 33.9% · T 66.1%
World TOPMed
G 35.2% · T 64.8%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

G/G Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Quoting this page

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Height (rs2327010). MyGeneLog™. https://www.mygenelog.com/variants/rs2327010

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