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Primary biliary cholangitis

CD80 · rs2293370

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Primary biliary cholangitis — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2011, PMID:21399635)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Primary biliary cholangitis. (GWAS Catalog, Nat Genet 2011, PMID:21399635)
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Primary biliary cholangitis compared to the general population. (GWAS Catalog, Nat Genet 2011, PMID:21399635)

Source: GWAS Catalog, Nat Genet 2011, PMID:21399635

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs2293370

What is rs2293370?

rs2293370 is a single position in the genome, in or near the CD80 gene. Published research associates it with primary biliary cholangitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs2293370?

Subjects that appear in the title or abstract of the same papers as this rsID include liver (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs2293370 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2293370 come from?

GWAS Catalog, Nat Genet 2011, PMID:21399635. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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