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Metabolic traits

CYP3A4 · rs17277546

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Metabolic traits compared to the general population. (GWAS Catalog, Nature 2011, PMID:21886157)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Metabolic traits. (GWAS Catalog, Nature 2011, PMID:21886157)
G/G Published research associates this genotype with typical/baseline likelihood of Metabolic traits — no copies of the reported risk allele. (GWAS Catalog, Nature 2011, PMID:21886157)

Source: GWAS Catalog, Nature 2011, PMID:21886157

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs17277546

What is rs17277546?

rs17277546 is a single position in the genome, in or near the CYP3A4 gene. Published research associates it with metabolic traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs17277546?

Subjects that appear in the title or abstract of the same papers as this rsID include bones and fractures (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs17277546 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs17277546 come from?

GWAS Catalog, Nature 2011, PMID:21886157. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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