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Gout

ABCG2 · rs1481012

Where this position leads

Condition: Gout

Drug: Statins

rs1481012 Condition: Gout Gout Condition Drug: Statins Statins Drug rs1481012 rs1481012 ABCG2

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gout compared to the general population. (GWAS Catalog, Nat Genet 2012, PMID:23263486)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gout. (GWAS Catalog, Nat Genet 2012, PMID:23263486)
G/G Published research associates this genotype with typical/baseline likelihood of Gout — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2012, PMID:23263486)

Source: GWAS Catalog, Nat Genet 2012, PMID:23263486

Questions about rs1481012

What is rs1481012?

rs1481012 is a single position in the genome, in or near the ABCG2 gene. Published research associates it with gout. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1481012 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does rs1481012 affect how medicines work?

ABCG2 carries pharmacogenomic findings for Statins. That is educational information, not a prescription or a dosing guide. Any decision to start, stop or change a medicine belongs with the clinician or pharmacist managing your treatment.

Does having rs1481012 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1481012 come from?

GWAS Catalog, Nat Genet 2012, PMID:23263486. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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