C/CPublished research associates this genotype with typical/baseline likelihood of Schizophrenia — no copies of the reported risk allele. (GWAS Catalog, JAMA Psychiatry 2013, PMID:23894747)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Schizophrenia. (GWAS Catalog, JAMA Psychiatry 2013, PMID:23894747)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Schizophrenia compared to the general population. (GWAS Catalog, JAMA Psychiatry 2013, PMID:23894747)
rs1261117 is a single position in the genome, in or near the TCF4 gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1261117 linked to?
On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.
Does having rs1261117 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1261117 come from?
GWAS Catalog, JAMA Psychiatry 2013, PMID:23894747. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.