Standard

Diabetic retinopathy

near PLXDC2 · rs12219125

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Diabetic retinopathy — no copies of the reported risk allele. (GWAS Catalog, Ophthalmology 2011, PMID:21310492)

G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Diabetic retinopathy. (GWAS Catalog, Ophthalmology 2011, PMID:21310492)

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Diabetic retinopathy compared to the general population. (GWAS Catalog, Ophthalmology 2011, PMID:21310492)

Source: GWAS Catalog, Ophthalmology 2011, PMID:21310492

Questions about rs12219125

What is rs12219125?

rs12219125 is a single position in the genome, in or near the near PLXDC2 gene. Published research associates it with diabetic retinopathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs12219125 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs12219125 come from?

GWAS Catalog, Ophthalmology 2011, PMID:21310492. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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