Links from this page to related variants, conditions, drugs and topics are not included for automated readers. Those connections are the Gene Knowledge Graph and are licensed as data: https://www.mygenelog.com/license

Standard

T1 FreeSurfer a2009s lh G front sup thickness

near MAPKAPK5 · rs11066074

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−8, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 7,058 Chinese Han ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.105 higher (95% confidence interval 0.07-0.141); p = 5 × 10−9.

Where it sits Chromosome 12, band 12q24.13 — between genes, 0.3 kb from MAPKAPK5.

How common each version is

GT
Korean KRGDB
G 76.4% · T 23.6%
Korean Korea4K
G 79.8% · T 20.2%
Korean Korea1K
G 78.3% · T 21.7%
Japanese ToMMo
G 84.8% · T 15.2%
World gnomAD
G 79.7% · T 20.3%
World 1000 Genomes
G 73.7% · T 26.3%
World TOPMed
G 79.8% · T 20.2%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

G/G No copy of the version the research linked to T1 FreeSurfer a2009s lh G front sup thickness. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to T1 FreeSurfer a2009s lh G front sup thickness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to T1 FreeSurfer a2009s lh G front sup thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Quoting this page

Licensed CC BY-NC 4.0: free to read, share and adapt for non-commercial use, naming MyGeneLog™ and linking the exact page. Commercial use, including training or serving a commercial AI system, needs a licence — https://www.mygenelog.com/license

T1 FreeSurfer a2009s lh G front sup thickness (rs11066074). MyGeneLog™. https://www.mygenelog.com/variants/rs11066074

← See all variants