C/CPublished research associates this genotype with typical/baseline likelihood of Psoriasis — no copies of the reported risk allele. (GWAS Catalog, PLoS Genet 2008, PMID:18369459)
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Psoriasis. (GWAS Catalog, PLoS Genet 2008, PMID:18369459)
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Psoriasis compared to the general population. (GWAS Catalog, PLoS Genet 2008, PMID:18369459)
rs10484554 is a single position in the genome, in or near the HLA-C gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10484554 linked to?
On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.
Does having rs10484554 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10484554 come from?
GWAS Catalog, PLoS Genet 2008, PMID:18369459. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.