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Solute carrier organic anion transporter family member 1B1
SLCO1B1 makes a gate on liver cells that pulls statins and some other medicines into the liver. A common change makes the gate work less well, so more of a statin stays in the blood, which raises the chance of muscle side effects with some statins.
Yes. Guidelines for some statins take SLCO1B1 into account, because a less active version raises statin levels in the blood. A doctor decides the medicine and dose.
No. Nothing here is a reason to start, stop or change a medicine. Talk to your doctor or pharmacist.
See SLCO1B1 with everything it connects to on the Gene Knowledge Graph, or as data at /api/v1/genes/SLCO1B1.
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SLCO1B1 gene. MyGeneLog™. https://www.mygenelog.com/genes/SLCO1B1
A gene page gathers published research; it is not a test result and not medical advice. If a gene matters to your health, talk to a doctor or a genetic counsellor.