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Eating Disorder, as genome-wide studies have reported it: 4 positions from 1 study, the largest recording 2,411 cases and 629,378 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
1 study in the GWAS Catalog report 4 positions for Eating Disorder, which the catalogue files as "Eating disorder (PheCode 305.2)". MyGeneLog follows the condition as positions arrive: code builds this page from the records, adds each new position when it is reported, and writes no sentence of its own beyond them.
Verma A et al. 2024, in Science — Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. The catalogue records its sample as 2,411 cases and 629,378 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). It contributes 4 positions: rs553488395 (LAMB1), rs575501818 (near COTL1P1), rs150212866 (near LINC02434), rs149524272 (near RNA5SP228). PMID:39024449.
The 4 positions lie in or near 4 genes: LAMB1, COTL1P1, LINC02434, RNA5SP228. A gene named here is the catalogue's mapped location for a position, not a mechanism; the studies are cited above so that a reader can go to them.
Verma A et al. 2024 reported the smallest P value on this page — P = 3 × 10-12 — at rs553488395 in LAMB1.
It is a record of what genome-wide studies have reported about Eating Disorder, kept current by code. It is not a description of the condition, an estimate of how common it is, or guidance of any kind — a page that took those from association records would be inventing them. Each variant page linked here carries that study's own record for the position in fixed sentences, and ClinVar's record where one exists.
Eating Disorder is diagnosed by a clinician — not from a genotype. None of the 4 variants on this page is used by any guideline to predict, screen for or diagnose it.
Everything here comes from population-level association records, put together by code. Those records compare groups of people; they do not examine anyone, and they give no guidance on care. For symptoms, testing or treatment, ask a clinician.
Databases, guidelines and references
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Eating Disorder. MyGeneLog™. https://www.mygenelog.com/conditions/eating-disorder
In the GWAS Catalog, Eating Disorder is filed as "Eating disorder (PheCode 305.2)". Rather than define it, this page lists the genome-wide findings: 4 positions from 1 study, each with its study's sample and citation.
Genome-wide studies have reported 4 associated positions; the largest study behind this page recorded 2,411 cases and 629,378 controls (African American or Afro-Caribbean ancestry, European ancestry, Hispanic or Latin American ancestry). Each common variant has a small effect, and an association in a population is not a cause in any one person.
The catalogue maps the positions to 4 genes: LAMB1, COTL1P1, LINC02434, RNA5SP228. These are where the positions sit, not proof of how they act.
No. They are population-level findings of small effect. Eating Disorder is diagnosed by a clinician, and no guideline uses a genotype to predict it.
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