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Cohen Syndrome, as genome-wide studies have reported it: 281 positions from 1 study. Assembled by code from the GWAS Catalog's records and kept current as positions arrive; every figure is the studies' own.
Genome-wide studies have so far placed 281 positions on Cohen Syndrome, from 1 study; the GWAS Catalog files the condition as "Cohen syndrome". MyGeneLog's code assembles this page from those records and rebuilds it when a new position is reported — nothing here was written by hand, and nothing here goes beyond what the records say.
A study. It contributes 281 positions: rs1014479884 (VPS13B), rs1057516287 (VPS13B), rs1057516331 (VPS13B), rs1057516422 (VPS13B), rs1057516484 (VPS13B), rs1057516489 (VPS13B), rs1057516494 (VPS13B), rs1057516559 (VPS13B), and 273 more.
The 281 positions sit in or beside 1 gene: VPS13B. These are locations, as the catalogue records them; whether any of these genes is how a position acts is a question the records leave open.
Association records say which positions differ, on average, between people with Cohen Syndrome and people without. They do not describe the condition, say how common it is, or tell anyone what to do, so this page does not either. For a single position, open its variant page: it gives that study's record in fixed sentences, with ClinVar's where there is one.
Cohen Syndrome is diagnosed by a clinician — not from a genotype. None of the 281 variants on this page is used by any guideline to predict, screen for or diagnose it.
This page was assembled by code from association records. It holds no clinical guidance, because its sources hold none: a genome-wide study reports which positions differ between people with a condition and people without, at the population level, and that is all this page repeats. A question about a symptom, a test or a treatment belongs with a clinician.
Databases, guidelines and references
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Cohen Syndrome. MyGeneLog™. https://www.mygenelog.com/conditions/cohen-syndrome
Cohen Syndrome is the condition the GWAS Catalog files under "Cohen syndrome". This page does not define it in its own words; it lists what genome-wide studies have reported: 281 positions from 1 study, with each study's sample and citation.
Genome-wide studies have reported 281 associated positions. Each common variant has a small effect, and an association in a population is not a cause in any one person.
The positions lie in or near 1 gene: VPS13B. A mapped gene is the catalogue's location for a position, not a mechanism.
No. Each variant shifts the odds only slightly, and only on average across many people. No guideline predicts Cohen Syndrome from a genotype; a clinician diagnoses it.
Free to reuse, non-commercially. This page's text is original writing from freely-available research, licensed CC BY-NC 4.0 — share and adapt it with attribution to MyGeneLog™; commercial use is licensed. It's general research-derived information, not medical advice or a diagnosis — see Terms of Use.