0 1616225Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot6Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others5Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Chronic Glomerulonephritis, NOS, as genome-wide studies have reported it: 16 positions from 1 study, the largest recording 667 cases and 571,939 controls (African American or Afro-Caribbean ancestry, European ancestry). Every figure comes from the studies themselves, gathered by code from the GWAS Catalog and updated as the records grow.
What this condition connects to
Prevalence
Not taken from these records, which report study sizes rather than how common the condition is. The largest study behind this page recorded 667 cases and 571,939 controls (African American or Afro-Caribbean ancestry, European ancestry) (Verma A et al. 2024, PMID:39024449).
Inheritance
Many positions, each with a small effect: 16 positions across 1 study, the pattern of a polygenic condition. The records do not give a heritability, and this page does not supply one.
Chronic Glomerulonephritis, NOS — filed in the GWAS Catalog as "Chronic glomerulonephritis, NOS (PheCode 580.14)" — is a condition this catalogue follows as its positions arrive. This page is assembled by MyGeneLog's own code from the catalogue's records and the studies' own listings: 16 positions from 1 study, and no sentence written by hand. It is rebuilt as new positions are reported, so what it says is what the records say today.
The studies behind the positions
Verma A et al. 2024, in Science — Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. The catalogue records its sample as 667 cases and 571,939 controls (African American or Afro-Caribbean ancestry, European ancestry). The 16 positions on this page from it: rs185537078 (near MIR3201), rs529217596 (PEX10), rs551919440 (near GPCPD1), rs116915466 (CDK14), rs192056986 (near LINC02947), rs189830598 (near RNA5SP199), rs180843162 (ADGRL2), rs557661665 (near DNAJB6), and 8 more. PMID:39024449.
Positions and mapped genes
The 16 positions sit in or beside 16 genes: MIR3201, PEX10, GPCPD1, CDK14, LINC02947, RNA5SP199, ADGRL2, DNAJB6, PRKN, CDH19, GPC6, ADIPOQ, COL4A4, RNA5SP169, CACNA1C, RPS6KA5. These are locations, as the catalogue records them; whether any of these genes is how a position acts is a question the records leave open.
Of all these, rs185537078 near MIR3201 carries the strongest signal: P = 4 × 10-13, in Verma A et al. 2024.
Reading this page
It is a record of what genome-wide studies have reported about Chronic Glomerulonephritis, NOS, kept current by code. It is not a description of the condition, an estimate of how common it is, or guidance of any kind — a page that took those from association records would be inventing them. Each variant page linked here carries that study's own record for the position in fixed sentences, and ClinVar's record where one exists.
Clinical detail
Genotype and diagnosis
Chronic Glomerulonephritis, NOS is diagnosed by a clinician — not from a genotype. None of the 16 variants on this page is used by any guideline to predict, screen for or diagnose it.
Everything here comes from population-level association records, put together by code. Those records compare groups of people; they do not examine anyone, and they give no guidance on care. For symptoms, testing or treatment, ask a clinician.
Related variants MyGeneLog™ checks for
What a 23andMe/AncestryDNA export or raw VCF can and can't tell you about Chronic Glomerulonephritis, NOS comes down to these specific, well-studied positions — not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
0 1616225Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot6Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others5Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Chronic Glomerulonephritis, NOS is the condition the GWAS Catalog files under "Chronic glomerulonephritis, NOS (PheCode 580.14)". This page does not define it in its own words; it lists what genome-wide studies have reported: 16 positions from 1 study, with each study's sample and citation.
Is Chronic Glomerulonephritis, NOS genetic?
Genome-wide studies have reported 16 associated positions; the largest study behind this page recorded 667 cases and 571,939 controls (African American or Afro-Caribbean ancestry, European ancestry). Each common variant has a small effect, and an association in a population is not a cause in any one person.
Which genes are linked to Chronic Glomerulonephritis, NOS on this page?
The positions lie in or near 16 genes: MIR3201, PEX10, GPCPD1, CDK14, LINC02947, RNA5SP199, ADGRL2, DNAJB6, PRKN, CDH19, GPC6, ADIPOQ, COL4A4, RNA5SP169, CACNA1C, RPS6KA5. A mapped gene is the catalogue's location for a position, not a mechanism.
Can these variants predict whether I will get Chronic Glomerulonephritis, NOS?
No. Each variant shifts the odds only slightly, and only on average across many people. No guideline predicts Chronic Glomerulonephritis, NOS from a genotype; a clinician diagnoses it.
Free to reuse. This page's text is original writing from freely-available research, licensed CC BY 4.0 — reuse it, including commercially, with attribution to MyGeneLog™. It's general research-derived information, not medical advice or a diagnosis — see Terms of Use.